An engineered Abcb4 expressing model reveals the central role of NF-κB in the regulation of drug resistance in zebrafish
C.-J. Sun, R.-Y. Hu, Z.-C. Li, L. Jin, C. Ye, H. Lu, Y.-H. Zhou, T. Zhou, Z.-X. He, L. Shu
This study creates a zebrafish model expressing Abcb4 to investigate drug resistance mechanisms, finding that NF-κB plays a central role in regulating Abcb4-mediated resistance.
bioRxiv · Mar 30, 2020 · PreprintZoology