The Wobble Uridine tRNA Writer MnmA Shapes Codon-Dependent Stress Response Systems
Humphrey Chukwudi Omeoga, Dylan J. Ehrbar, Chetna Mathur, Cady Roselli, Katherine Urner, Evan T. Davis, Rizwan Ahmad, Agnieszka Dziergowska, Qishan Lin, Peter C. Dedon, Jia Sheng, Thomas J. Begley
This study identifies MnmA as a key enzyme that regulates codon-dependent stress response systems in E. coli by affecting tRNA modifications and gene expression.
bioRxiv · Aug 19, 2026 · PreprintMolecular Biology