Conformational landscape and clustering of human type 2 IP3 receptor in lipid nanodiscs
Caifeng Liu, Yu-Jing Lan, Qingyu Tang, Erkan Karakaş
The paper determines cryo-EM structures of human IP3R-2 in different conformations and clusters, revealing ligand interactions and subtype-specific features.
bioRxiv · Feb 1, 2026 · PreprintBiophysics