Single-Cell Sequencing Identifies the Crucial Role of Mitochondrial Fission-Fusion Balance in Cardiac Hypertrophy Progression
Tao He, Jianmei Sha, Yuxin Hu, Caihong Shao, Yi Zhou, Chen Lü, Jianhua Yao, Junli Gao
The paper uses single-cell and bulk RNA sequencing to compare pathological and physiological cardiac hypertrophy, finding that mitochondrial fission genes drive pathological progression.
bioRxiv · Feb 13, 2025 · PreprintBioinformatics