Single-cell transcriptomics and machine learning reveal RNF144B and C5AR1 as immune-related biomarkers and therapeutic targets in myocardial infarction
Yuxin Hu, Lü Chen, Jianmei Sha, Cai-hong Shao, Junli Gao, Jianhua Yao
This paper identifies a 13-gene signature, including RNF144B and C5AR1, associated with myocardial infarction through transcriptomics and machine learning, highlighting their role in immune modulation and suggesting CCX168 as a therapeutic candidate.
bioRxiv · Sep 3, 2025 · PreprintCell Biology