Escape from SARS-CoV-2 Nsp1-mediated host shutoff by TIAR transcript reveals general features of Nsp1 resistance
Caleb Galbraith, Madeleine Stolz, Scott Tersteeg, Emily Andrews, Trushar R. Patel, Denys A. Khaperskyy
The paper identifies sequence features in the TIAR 5' UTR that confer resistance to SARS-CoV-2 Nsp1 host shutoff, revealing shared characteristics with viral leader sequences.
RNA · Dec 17, 2025Peer-reviewedMolecular Biology