WHEP Domain of Glycyl-tRNA Synthetase Regulates Neuropilin 1 Binding and Vascular Permeability
Yao Tong, Noemi Gioelli, Huimin Zhang, Calin Dan Dumitru, Sachiko Kanaji, Motoki Horii, Ka Neng Cheong, Jiadong Zhou, Brad N. Bolon, Ge Bai, Guido Serini, Taisuke Kanaji, Xiang‐Lei Yang
This study shows that the WHEP domain of GlyRS regulates Nrp1 binding and vascular permeability, affecting lung development and vascular leakage in mice.
bioRxiv · May 14, 2025 · PreprintMolecular Biology