Xiang‐Lei Yang

The paper reveals a cross-regulation between translation and NAD+ metabolism through the interaction of SerRS and SIRT2, mediated by ADP-ribose.

This study shows that the WHEP domain of GlyRS regulates Nrp1 binding and vascular permeability, affecting lung development and vascular leakage in mice.

AARS Online provides a curated database of aminoacyl-tRNA synthetases with sequence, structure, and evolutionary information, accessible via an interactive platform.

The paper shows TyrRS mediates a late integrated stress response by inhibiting translation and protecting cells from prolonged stress through nuclear translocation.

The paper shows that mutant GlyRS disrupts Nrp1/VEGF-A signaling but does not affect vascular development or maintenance in CMT2D mice.