BioinformaticsJCI InsightPeer-reviewed
Joint-specific rheumatoid arthritis fibroblast-like synoviocyte regulation identified by integration of chromatin access and transcriptional activity
Eunice Choi, Camilla R.L. Machado, T. Okano…·Gary S. Firestein
The paper identifies joint-specific regulatory patterns in rheumatoid arthritis fibroblast-like synoviocytes by integrating chromatin accessibility and transcriptional data, revealing differences in proliferation, migration, and inflammation between hand and non-hand joints.
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