Author

David Boyle

University of California San DiegoORCID 0000-0003-3352-5092Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Gary S. FiresteiniD· 2 shared Aaron Wise· 1 shared Accelerating Medicines Partnership: RA/SLE Network· 1 shared Adam T. Chicoine· 1 shared Alexander Yu RudenskyiD· 1 shared Ami Ben-Artzi· 1 shared Amit LakhanpaliD· 1 shared Andrew Cordle· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Gary S. FiresteinORCID

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2 papers

Recent·Most cited

ImmunologyScience Translational MedicinePeer-reviewedJun 24, 2026

SPP1hi macrophages in fibrin niches promote hyperplastic tissue remodeling in rheumatoid arthritis synovium

Ian Mantel, Haoxuan Zhang, Juan Vargas…·Thomas Eisenhaure

SPP1hi macrophages in RA synovial fibrin deposits promote tissue hyperplasia.

4 citationstop 1%

humanspatial transcriptomics

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BioinformaticsJCI InsightPeer-reviewedMay 23, 2024

Joint-specific rheumatoid arthritis fibroblast-like synoviocyte regulation identified by integration of chromatin access and transcriptional activity

Eunice Choi, Camilla R.L. Machado, T. Okano…·Gary S. Firestein

The paper identifies joint-specific regulatory patterns in rheumatoid arthritis fibroblast-like synoviocytes by integrating chromatin accessibility and transcriptional data, revealing differences in proliferation, migration, and inflammation between hand and non-hand joints.

19 citationstop 3%

humanbulk RNA-seq

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