Design of Novel Dehalogenases using Protein Large Language Models
Lucas Garcia, Willow Nauber, Camille Dahlgren, Ray Chung, Troy Reyes, Jael Santos, Maya Kapur, Monica Barsever, Matt W. Thomson, Alec Lourenço
High school students designed novel dehalogenases using large language models to degrade PFOA, a persistent PFAS compound, and plan to test their enzymatic activity.
bioRxiv · Oct 28, 2024 · PreprintBioengineering