Author

Lucas Garcia

Duke University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:proteomics· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Alec Lourenço· 1 shared Alessandro De SimoneiD· 1 shared Ashley RichiD· 1 shared Camille Dahlgren· 1 shared Jacqueline JansseniD· 1 shared Jael Santos· 1 shared Jianhong OuiD· 1 shared Kazunori AndoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

Alec Lourenço

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2 papers

Recent·Most cited

Decaying and expanding Erk gradients process memory of skeletal size during zebrafish fin regeneration

Ashley Rich, Ziqi Li, Alessandro De Simone, Lucas Garcia, Jacqueline Janssen, Kazunori Ando, Jianhong Ou, Massimo Vergassola, Kenneth D. Poss, Stefano Di Talia

The paper quantifies Erk signaling gradients in zebrafish fin regeneration and shows they scale with tissue amputation size to control skeletal regeneration.

Nature Physics · Jul 6, 2026Peer-reviewedDevelopmental Biology

Design of Novel Dehalogenases using Protein Large Language Models

Lucas Garcia, Willow Nauber, Camille Dahlgren, Ray Chung, Troy Reyes, Jael Santos, Maya Kapur, Monica Barsever, Matt W. Thomson, Alec Lourenço

High school students designed novel dehalogenases using large language models to degrade PFOA, a persistent PFAS compound, and plan to test their enzymatic activity.

bioRxiv · Oct 28, 2024 · PreprintBioengineering