GAS7 coordinates the activity of RAC1 and CDC42 to enhance macropinocytic surveillance and suppress motility in macrophages
Anaël Hanouna, Mabel J. Jouve, Victorine Hilly, Sarah Taheraly, François-Xavier Gobert, Mathieu Maurin, Camille Petit, Emma Granier, Philippe Benaroch, Vasco Rodrigues
This study identifies GAS7 as an F-BAR protein that coordinates RAC1 and CDC42 to enhance macropinocytic uptake and suppress motility in macrophages.
bioRxiv · Dec 11, 2025 · PreprintCell Biology