Proteomic characterisation of three independent series of sequential cystic fibrosis strains in an international Pseudomonas aeruginosa reference panel indicates positive selection in late infection strains.
Joanna Drabinska, Lucia O’ Connor, Caoilin McClean, Siobhán McClean
The paper identifies proteins that show increased abundance in late-stage Pseudomonas aeruginosa isolates from CF patients, suggesting positive selection and adaptation to chronic infection.
bioRxiv · Feb 14, 2025 · PreprintMicrobiology