Human RAMP1 overexpressing mice are resistant to migraine therapies for motion sensitivity
Shafaqat M. Rahman, Linda Guo, Carissa Minarovich, Laura Moon, Anna A. Guo, Anne E. Luebke
This study shows that overexpressing human RAMP1 in mice increases CGRP signaling and makes them resistant to migraine treatments like olcegepant and rizatriptan.
PLoS ONE · Dec 9, 2024Peer-reviewedNeuroscience