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Carla M. Kumbale

Georgia Institute of Technology

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Approach:statistical model· 1

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Eberhard O. VoitiD· 1 shared Qiang ZhangiD· 1 shared

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Systems BiologyBiomoleculesPeer-reviewedNov 22, 2021

Emergence and Enhancement of Ultrasensitivity through Posttranslational Modulation of Protein Stability

Carla M. Kumbale, Eberhard O. Voit, Qiang Zhang

The paper models how posttranslational modifications affect protein stability and signal amplification, showing that stabilization can enhance ultrasensitivity and alter response dynamics.

5 citations

statistical model