Eberhard O. Voit

The paper models how posttranslational modifications affect protein stability and signal amplification, showing that stabilization can enhance ultrasensitivity and alter response dynamics.

This study compares Lotka-Volterra and Multivariate Autoregressive models for ecological interaction systems, finding LV models generally superior for dynamic data with large deviations from steady states.

The paper infers and validates interaction parameters in Lotka-Volterra models using two new strategies and assesses data compliance with LV structure.

This paper introduces DISCO, a method to infer single-cell signaling dynamics from snapshot data, revealing cell-to-cell variation in MAPK/ERK signaling and its dependence on initial states.

The paper develops a computational model of the phosphoinositide pathway in mammalian cells, showing it replicates steady-state and dynamic phenomena and identifies key contributors to PI(4,5)P2 production.