Sex-dependent hypothalamic microinflammation and microglial polarization: The role of JNK in high-fat diet-induced insulin resistance
Maria Rodriguez-Garcia, Montserrat Bolaños-Hurtado, Aina Redondo, Carmé Caelles, Melania González-Torres, Elisenda Sanz, Albert Quintana, Sebastián Zagmutt, Rosalía Rodríguez‐Rodríguez
This study investigates sex-specific hypothalamic microinflammation and microglial polarization in response to high-fat diet, identifying JNK3 as a key regulator of these processes in males.
bioRxiv · Nov 11, 2025 · PreprintNeuroscience