Hippocampal reactivation of aversive experience enables safety learning and slow-breathing state for recovery from stress
Baptiste Mahéo, Sophie Bagur, Dmitri V. Bryzgalov, Chloé Hayhurst, Mathilde Chouvaeff, Ella Callas, Carole Schmidt, Thierry Gallopin, Karim Benchenane
The paper identifies a slow-breathing recovery state in mice after threat avoidance, linked to hippocampal replay of aversive experiences and impaired by SWR suppression.
bioRxiv · Jun 3, 2025 · PreprintNeuroscience