Integrative genomics elucidates the evolutionary, temporal, and developmental origins of a hydrocephalus risk gene
Andrew T. Hale, Yuwei Song, Caroline Davies, Shanrun Liu, Regan E. Gaskin, Anastasia Arynchyna-Smith, Brandon George Rocque, Zechen Chong
The paper characterizes the evolutionary origin and expression of MAEL in the developing human brain and finds reduced MAEL expression in hydrocephalus brain tissue.
Experimental Neurology · Mar 12, 2026Peer-reviewedGenetic & Genomic Medicine