Andrew T. Hale

The paper characterizes the evolutionary origin and expression of MAEL in the developing human brain and finds reduced MAEL expression in hydrocephalus brain tissue.

The paper identifies TMEM208 as a transcriptome-wide predictor of hydrocephalus in African ancestry patients, linking it to inflammation and infection pathways.

This study shows IPMK regulates HDAC3 activity and histone H4 acetylation in human cells through inositol phosphate production.

This review summarizes the genetic basis of hydrocephalus, including genes, pathways, and mechanisms, to highlight the complexity and global impact of its genetic contributions.

This study uses endoluminal tissue sampling to analyze genetic and transcriptional features of vein of Galen malformation endothelial cells.

The paper identifies genetic variants in RASA1 and EPHB4 associated with vein of Galen malformations through exome analysis and single-cell transcriptomics.

This study identifies a novel genetic locus, FGD6, associated with intracranial aneurysm rupture through GWAS and functional genomics analysis.

This paper conducts a genome-wide association study (GWAS) to identify genetic risk factors for trigeminal neuralgia, finding two significant loci associated with the condition.

The paper identifies 70 gene-level associations with 26 infectious disease traits using transcriptome-wide association studies and explores their molecular basis and implications for host-pathogen interactions.