Rebound activation of 5-HT neurons following SSRI discontinuation
Helen Collins, L. Sophie Gullino, Dersu Ozdemir, Caroline Lazarenco, Yulia Sudarikova, Elizabeth Daly, Fuencisla Pilar-Cuéllar, Raquel Pinacho, David M. Bannerman, Trevor Sharp
This study shows that stopping SSRIs like paroxetine leads to increased 5-HT activity in the brain, causing anxiety-like behaviors and changes in neurotransmitter levels.
Neuropsychopharmacology · Apr 12, 2024Peer-reviewedNeuroscience