Afterload-induced Decreases in Fatty Acid Oxidation Develop Independently of Increased Glucose Utilization
Hande C. Piristine, Herman I. May, Nan Jiang, Daniel Daou, Francisco Olivares-Silva, Abdallah Elnwasany, Pamela A. Szweda, Luke I. Szweda, Caroline S. Kinter, Michael T Kinter, Gaurav Sharma, Xiaodong Wen, Craig R. Malloy, Michael Erik Jessen, Thomas G. Gillette, Joseph A. Hill
This study shows that reduced glucose utilization in heart failure with preserved ejection fraction does not lead to increased fatty acid oxidation, even when glucose availability is limited.
bioRxiv · Sep 17, 2024 · PreprintCell Biology