Deletion of core septin gene aspB in Aspergillus fumigatus results in fungicidal activity of caspofungin
Rebecca Jean Busch, Carson Doty, C. Allie Mills, Flutur Latifi, Laura E. Herring, Vjollca H. Konjufca, Francisco R. Carvallo, Tatiana Boluarte, José M. Vargas-Muñiz
This study shows that deletion of the septin gene aspB in Aspergillus fumigatus makes it susceptible to the fungistatic drug caspofungin, converting it to a fungicidal effect.
Molecular Biology of the Cell · Sep 16, 2026Peer-reviewedMicrobiology