Cell vulnerability within the sublaterodorsal tegmental nucleus underlies REM sleep behaviour disorder in prodromal α-synucleinopathy
Russell Luke, Han Soo Yoo, Dillon McKenna, Andrea M Bevan, Casey Durso, Brittany J Dugan, Yuling Liang, Bardia Amanirad, Jefferson A. Steltz, Bin Zhang, Allison Yearwood, Jonah Lourie, Phil Hyu Lee, Jimmy J. Fraigne, John H. Peever, Kelvin C. Luk
The paper shows that synucleinopathy in SLD glutamatergic neurons causes RBD and Parkinson's-like deficits in mice.
bioRxiv · May 1, 2026 · PreprintNeuroscience