Neuroprotective efficacy of the glucocorticoid receptor modulator PT150 in the rotenone mouse model of Parkinsons disease
Amanda S. Latham, Savannah M. Rocha, Casey P. McDermott, Philip Reigan, Richard A. Slayden, Ronald B. Tjalkens
This study evaluates the neuroprotective effects of PT150, a glucocorticoid receptor modulator, in a rotenone-induced Parkinson's disease mouse model, showing reduced dopaminergic neuron loss and α-synuclein accumulation.
NeuroToxicology · Jul 1, 2024Peer-reviewedNeuroscience