Ronald B. Tjalkens

Microglia-specific NF-κB signaling is a critical regulator of prion-induced glial inflammation and neuronal loss

This study shows that microglial NF-κB signaling is critical for prion disease progression, with IKK KO microglia leading to faster disease onset and neuronal loss.

Sex specific effects of environmental toxin-derived alpha synuclein on enteric neuronal-epithelial interactions

This study investigates sex-specific effects of environmental toxin-derived alpha synuclein on enteric neuronal-epithelial interactions in a mouse model of Parkinson's Disease, finding increased aSyn and CGRP immunoreactivity in females.

Discrimination of Jamaican fruit bat lymphocytes by flow cytometry

The paper identifies cross-reactive monoclonal antibodies for profiling Jamaican fruit bat lymphocytes and generates specific antibodies for CD3γ, CD4, and CD8 to enable flow cytometry analysis of T cells.

Neuroprotective efficacy of the glucocorticoid receptor modulator PT150 in the rotenone mouse model of Parkinsons disease

This study evaluates the neuroprotective effects of PT150, a glucocorticoid receptor modulator, in a rotenone-induced Parkinson's disease mouse model, showing reduced dopaminergic neuron loss and α-synuclein accumulation.