Author

Catalina A Vallejos

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Genomics· 1

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Approach:Bayesian inference· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

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John C Marioni· 1 shared Sylvia Richardson· 1 shared

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2016-2016 · peak 1/yr

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John C Marioni

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1 paper

Recent·Most cited

GenomicsbioRxivJan 5, 2016

Beyond comparisons of means: understanding changes in gene expression at the single-cell level

Catalina A Vallejos, Sylvia Richardson, John C Marioni

This paper introduces a Bayesian hierarchical model to detect changes in gene expression beyond mean comparisons in scRNA-seq data, revealing differences in cell-to-cell heterogeneity.

DOI 10.1186/s13059-016-0930-3

mousescRNA-seq

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