Author

Sylvia Richardson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:Bayesian inference· 2 Research Focus:differential expression· 1 Research Focus:fine-mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Antony J Cutler· 1 shared Arcadio Rubio Garcia· 1 shared Catalina A Vallejos· 1 shared Chris WallaceiD· 1 shared Deborah J Smyth· 1 shared Hui Guo· 1 shared Jason D Cooper· 1 shared John C Marioni· 1 shared

Activity by Year

2015-2016 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetics

Antony J Cutler

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2 papers

Recent·Most cited

Beyond comparisons of means: understanding changes in gene expression at the single-cell level

Catalina A Vallejos, Sylvia Richardson, John C Marioni

This paper introduces a Bayesian hierarchical model to detect changes in gene expression beyond mean comparisons in scRNA-seq data, revealing differences in cell-to-cell heterogeneity.

bioRxiv · Jan 5, 2016Genomics

Dissection of a complex disease susceptibility region using a Bayesian stochastic search approach to fine mapping

Chris Wallace, Antony J Cutler, Nikolas Pontikos, Marcin L Pekalski, Oliver S Burren, Jason D Cooper, Arcadio Rubio Garcia, Ricardo C Ferreira, Hui Guo, Neil M Walker, Deborah J Smyth, Stephen S Rich, Suna Onengut-Gumuscu, Stephen S Sawcer, Maria Ban, , Linda Wicker

This study uses a Bayesian stochastic search method to fine map genetic variants in the IL-2RA region associated with multiple sclerosis and type 1 diabetes, identifying shared causal variants.

PLOS Genetics · Jun 24, 2015Peer-reviewedGenetics