Computational insights on the destabilizing mutations in the binding site of 3CL-protease SARS-CoV-2 Omicron (VOC)
Samee Ullah, Afreenish Amir, Aamer Ikram, Caterina Vicidomini, Rosanna Palumbo, Giovanni Nicola Roviello
This study computationally analyzes mutations in the 3CL-protease binding site of the SARS-CoV-2 Omicron variant, showing reduced drug effectiveness due to structural changes.
bioRxiv · May 24, 2023 · PreprintBioinformatics