Aamer Ikram

The paper identifies a nine-marker signature of lapatinib resistance in HER2-positive breast cancer using integrative multi-omics analysis, revealing novel biomarkers and chromatin dynamics associated with drug resistance.

The paper introduces TyphiNET, a dashboard for exploring Typhi genomics data to support public health decisions on antimicrobial resistance and vaccine implementation.

This study computationally analyzes mutations in the 3CL-protease binding site of the SARS-CoV-2 Omicron variant, showing reduced drug effectiveness due to structural changes.

This study performs in silico analysis of SARS-CoV-2 spike proteins from different variants to identify structural and functional variations.

This study characterizes SARS-CoV-2 genomic diversity in Islamabad, Pakistan, during November-December 2021, identifying Omicron BA.1, Lineage A, and Delta AY.27 variants.

This study analyzes the binding mechanism of the SARS-CoV-2 Omicron variant's spike protein to the ACE2 receptor, revealing enhanced binding affinity and novel interactions compared to wild-type and Delta variants.

This study validates RT-LAMP as a rapid, cost-effective alternative to RT-qPCR for COVID-19 testing in Pakistan, showing high sensitivity but lower concordance with weak RT-qPCR signals.