Advantage of the F(ab)'2 fragment over IgG for RIT and PRIT
Zainab Tabaja, Maya Diab, Frédérique Nguyen, Catherine Maurel, Frédéric Pecorari, Sylvia Lambot, François Davodeau
This paper compares the therapeutic index of IgG and F(ab)2 fragments in preclinical radioimmunotherapy models, finding F(ab)2 improves therapeutic outcomes.
bioRxiv · Oct 16, 2024 · PreprintCancer Biology