Synaptic sign switching mediates online dopamine updates
Shun Li, Wengang Wang, Grace Knipe, Elliot Jerng, Paolo Capelli, Catherine Zhou, Eliana Bilsel, Bernardo Luis Sabatini
The paper shows that synaptic sign switching mediates dopamine updates and contributes to reinforcement learning by altering synaptic signs and weights in EP-LHb synapses.
bioRxiv · Jul 23, 2025 · PreprintNeuroscience