FoxO1 and HNF1α cooperatively remodel nucleosome architecture and mechanical stability to activate transcription
Alfredo Jose Florez Ariza, Zhenlin Yang, Robert P Sosa, Cesar Diaz-Cellis, Hannah J Richter, Vijay Ramani, Carlos J. Bustamante, Eva Nogales
This study shows FoxO1 and HNF1α work together to change nucleosome structure and stability to activate transcription.
bioRxiv · Nov 3, 2026 · PreprintBiophysics