CD47 blockade enhances immunoradiotherapy response in head and neck squamous cell carcinoma
Abdula Monther, Riyam Al Msari, Robert Saddawi‐Konefka, Santiago Fassardi, Cynthia Y. Tang, Chad Philips, Prakriti Sen, Pardis Mohammadzadeh, Kelsey Decker, Sayuri Miyauchi, Roy S, Riley N. Jones, Jorge Silvio Gutkind, Andrew B. Sharabi, Joseph A. Califano
This study shows CD47 blockade combined with anti-PD1 and radiotherapy improves tumor response in HNSCC by enhancing antigen presentation and immune cell infiltration.
bioRxiv · Jun 29, 2025 · PreprintCancer Biology