Engineering large chromosomal deletions by CRISPR-Cas9
Thomas F. Eleveld, Chaimaa Bakali, Paul P. Eijk, Phylicia Stathi, Lianne E. M. Vriend, Pino J. Poddighe, Bauke Ylstra
This paper describes a CRISPR-Cas9 method to engineer arm-level chromosomal deletions in neuroblastoma cell lines to study their oncogenic role.
Nucleic Acids Research · Jun 14, 2021Peer-reviewedGenetics