Author

Thomas F. Eleveld

Amsterdam University Medical CentersORCID 0000-0001-8580-4822Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:perturbation response prediction· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Ad J.M. Gillis· 1 shared Andrew Green· 1 shared Annelore Van Der KeleniD· 1 shared Ashwin Ramdien· 1 shared Bauke YlstraiD· 1 shared Carli M. Tops· 1 shared Chaimaa Bakali· 1 shared Claire PallesiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCancer Biology

Ad J.M. Gillis

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3 papers

Recent·Most cited

Cancer BiologyCommunications MedicinePeer-reviewedApr 17, 2026

Identification and validation of liquid biopsy-based methylation biomarkers: a germ cell tumor subtype-specific study

Ferdinand W. Janssen, Ad J.M. Gillis, Puck B. Gouswaart…·Leendert H. J. Looijenga

This study identifies and validates methylation biomarkers for YST subtype-specific liquid biopsy in germ cell tumors using DNA methylation data and qPCR validation.

2 citationstop 2%

humanDNA methylation

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Genetic & Genomic MedicineHuman Genetics and Genomics AdvancesPeer-reviewedJul 18, 2025

Clinical syndromes linked to biallelic germline variants in MCM8 and MCM9

Noah C. Helderman, Ting Yang, Claire Palles…·Margot Julia Wyrwoll

This study identifies biallelic germline variants in MCM8 and MCM9 as linked to polyposis, gastric cancer, early-onset colorectal cancer, and hypogonadism, with MCM9 variants showing stronger associations.

3 citations

humanwhole-exome sequencing

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GeneticsNucleic Acids ResearchPeer-reviewedJun 14, 2021

Engineering large chromosomal deletions by CRISPR-Cas9

Thomas F. Eleveld, Chaimaa Bakali, Paul P. Eijk…·Bauke Ylstra

This paper describes a CRISPR-Cas9 method to engineer arm-level chromosomal deletions in neuroblastoma cell lines to study their oncogenic role.

38 citations

humanexperimental assay

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