Compact Oligomerized-Motif Promoters for Adjustable Control of Transcription (COMPACT) for Robust, Tunable and Bidirectional Gene Expression in Mammalian Cells
Chaja Katzman, Sharon Matusevich, Shir-Liya Dadon, Keren Roas, Tamar Aminov, Renana Yulis, Natella Buketov, Tzlil Yair, Tali Lanton, Bar Zaruk, Oren Ram, Lior Nissim
The paper introduces COMPACT promoters for tunable and robust gene expression in mammalian cells, showing they outperform native promoters under stress conditions.
bioRxiv · Aug 19, 2026 · PreprintSynthetic Biology