PRMT5 regulates ovarian follicle development by facilitating Wt1 translation
Min Chen, Fangfang Dong, Min Chen, Zhiming Shen, Haowei Wu, Changhuo Cen, Xiuhong Cui, Shilai Bao, Fei Gao
This study shows PRMT5 promotes ovarian follicle development by enhancing Wt1 translation through methylation of HnRNPA1, leading to proper granulosa cell function and fertility.
eLife · Aug 27, 2021Peer-reviewedDevelopmental Biology