Fei Gao

Inhibition of Endocannabinoid Degradation in Astrocytes Reprograms Glial Reactivity and Prevents Seizure Sequelae

This study shows that inhibiting MAGL in astrocytes reduces seizures and neuroinflammation by activating CB1-PPAR-γ signaling, preserving synaptic function and preventing cognitive decline in epilepsy.

Tmc7 deficiency causes acrosome biogenesis defects and male infertility in mice

This study shows that Tmc7 deficiency in mice causes acrosome biogenesis defects and male infertility by disrupting Golgi function and ion homeostasis.

The longitudinal single-cell panorama of cynomolgus monkey ovary throughout lifespan revealed a conserved ovarian clock between primates

The paper constructs a longitudinal single-cell atlas of cynomolgus monkey ovaries across 22 years, identifies a novel oocyte type, and develops a transcriptomic ovarian clock applicable to humans.

CircSry regulates spermatogenesis by enhancing γH2AX expression via sponging miR-138-5p

This study identifies circSry as a regulator of spermatogenesis by enhancing γH2AX expression through miR-138-5p sponging in mouse testis.

PRMT5 regulates ovarian follicle development by facilitating Wt1 translation

This study shows PRMT5 promotes ovarian follicle development by enhancing Wt1 translation through methylation of HnRNPA1, leading to proper granulosa cell function and fertility.

The role of Cyp19a1 in female pathway of a freshwater turtle (Mauremys reevesii) with temperature-dependent sex determination

Somatic cell-derived BMPs induce male germ cell meiosis initiation during embryonic stage via regulating Dazl expression

This study shows that BMP signaling from somatic cells induces meiosis in male germ cells by increasing Dazl expression during embryonic development.