Author

Changxian Xiong

Peking University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Bingwei WangiD· 2 shared Daotong LiiD· 2 shared Jiarui LiuiD· 2 shared Ruimao ZhengiD· 2 shared Shizhang WeiiD· 2 shared Yujia Hou· 2 shared Yun ZhaoiD· 2 shared Miao ZhaoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 35 mutual co-author links

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2 shared papersBioinformatics

Bingwei WangORCID

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2 papers

Recent·Most cited

The discovery of phages in the Substantia Nigra and its implication for Parkinson's Disease

Yun Zhao, Changxian Xiong, Bingwei Wang, Daotong Li, Jiarui Liu, Shizhang Wei, Yujia Hou, Yuan Zhou, Ruimao Zheng

The paper identifies phages in the human substantia nigra and links their presence to Parkinson's Disease pathogenesis through virome analysis and gene expression correlation.

Research · Jan 1, 2025Peer-reviewedBioinformatics

Age-related decline of PKA-RIIβ level in SNc dopaminergic neurons underlies PD pathogenesis

Yun Zhao, Bingwei Wang, Miao Zhao, Jiarui Liu, Yujia Hou, Shizhang Wei, Changxian Xiong, Daotong Li, Ruimao Zheng

The paper identifies a decline in PKA-RIIβ levels in SNc dopaminergic neurons of PD patients and shows that restoring PKA-RIIβ alleviates parkinsonism in mice.

bioRxiv · Sep 13, 2024 · PreprintNeuroscience