Yuan Zhou

The paper establishes the Human NK-cell Atlas and identifies disease-specific NK-cell state remodeling, developing a model to predict clinical phenotypes.

The paper identifies novel m6A readers that regulate human embryonic stem cell differentiation through comprehensive profiling of m6A readouts across multiple cell lines.

This paper identifies and predicts O-glycosylated RNA using a chemoenzymatic method and a computational tool, revealing their role in pancreatic cancer progression.

RNANO predicts multiple RNA modifications from nanopore DRS data with high accuracy, detecting seven modification types in human cells.

This study shows METTL3 promotes VSMC proliferation and neointima formation by enhancing SGK1 transcription through m6A-YTHDC1 mechanism.

The paper identifies phages in the human substantia nigra and links their presence to Parkinson's Disease pathogenesis through virome analysis and gene expression correlation.

The paper models a microRNA-derived disease network to identify methotrexate as a potential therapy for abdominal aortic aneurysm in mice.

This study identifies 532 ASD-related lncRNAs, validates 86.7% with CNV data, and explores their functions and pathways in autism.

RPRH infers potential roles of plant miRNAs in humans and profiles their regulatory functions using a database of 10414 miRNAs and 18062 annotations.

DrugPattern is a web-based tool that performs drug set enrichment analysis to identify patterns in drug-related datasets, revealing unexpected protective roles of oxLDL in diseases.

GIC predicts the essentiality of protein-coding genes and lncRNAs using RNA sequence data, achieving high performance for lncRNAs in a mouse dataset.