NeurosciencebioRxivPreprint
Age-related decline of PKA-RIIβ level in SNc dopaminergic neurons underlies PD pathogenesis
Yun Zhao, Bingwei Wang, Miao Zhao…·Ruimao Zheng
The paper identifies a decline in PKA-RIIβ levels in SNc dopaminergic neurons of PD patients and shows that restoring PKA-RIIβ alleviates parkinsonism in mice.
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