Epithelial-mesenchymal cell state heterogeneity predetermines differential phospho-signaling responses to epidermal growth factor stimulation
Felix V Kohane, Chantelle Johnstone, Daniel Neumann, Ihuan Gunawan, Tim Huang, Fatemeh Vafaee, Christine Louise Chaffer, John George Lock
The paper shows that pre-existing epithelial-mesenchymal (E/M) cell states determine differential phospho-signaling responses to EGF in NSCLC cells.
Molecular Biology of the Cell · Dec 3, 2025Peer-reviewedCancer Biology