BMAL2 is a druggable target for ARID1A-wildtype ovarian clear cell carcinoma (OCCC)
Grace Y.T. Tan, Pei-Yi Lin, Li-Tzu Cheng, Yu-Sheng Tsai Yuan, Shih‐Han Huang, Chen-Hsin Albert Yu, Chao-Tsen Chen, Peter Chi, Wendy W. Hwang‐Verslues
This study identifies BMAL2 as a therapeutic target for ARID1A-wt ovarian clear cell carcinoma, showing that its depletion or degradation reduces tumor growth and DNA damage.
bioRxiv · Oct 21, 2025 · PreprintCancer Biology