Author

Chaoyu Lei

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Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Baosheng N/A FengiD· 1 shared Chang Chen· 1 shared Jiatao Li· 1 shared Lei Liu· 1 shared Lei Sun· 1 shared Manman Yang· 1 shared Qigang Li· 1 shared Qin YaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Baosheng N/A FengORCID

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1 paper

Recent·Most cited

Assessing and Optimizing Low-Frequency Somatic Mutation Detection: A Multi-Platform High-Throughput Sequencing Perspective

Baosheng N/A Feng, Yixin Lin, Lei Liu, Qunting Lin, Yuan Lin, Yongfang Liu, Jiatao Li, Chaoyu Lei, Chang Chen, Manman Yang, Xuejie Peng, Zhiliang Zhou, Qin Yan, Lei Sun, Qigang Li

This study evaluates and improves low-frequency somatic mutation detection across multiple sequencing platforms using a simulated benchmark and a machine learning-based caller.

bioRxiv · Jun 3, 2026 · PreprintBioinformatics