Author

Manman Yang

Primary ORCID profile (0000-0003-4328-056X · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Manman YangiD3 papers · BGI Group (China)

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Lei Liu· 2 shared Lei Sun· 2 shared Qigang Li· 2 shared Qin YaniD· 2 shared Qunting Lin· 2 shared Xuejie Peng· 2 shared Baosheng Feng· 1 shared Baosheng N/A FengiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersBioinformatics

Lei Liu

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2 papers

Recent·Most cited

Assessing and Optimizing Low-Frequency Somatic Mutation Detection: A Multi-Platform High-Throughput Sequencing Perspective

Baosheng N/A Feng, Yixin Lin, Lei Liu, Qunting Lin, Yuan Lin, Yongfang Liu, Jiatao Li, Chaoyu Lei, Chang Chen, Manman Yang, Xuejie Peng, Zhiliang Zhou, Qin Yan, Lei Sun, Qigang Li

This study evaluates and improves low-frequency somatic mutation detection across multiple sequencing platforms using a simulated benchmark and a machine learning-based caller.

bioRxiv · Jun 3, 2026 · PreprintBioinformatics

CMS: Achieving Uniform and High-Quality Sequencing across Challenging Non-canonical Genomic Regions

Qigang Li, Lei Liu, Qunting Lin, Xu Dan, Yuzhou Jiang, Yanli Wei, Manman Yang, Xuejie Peng, Weiwei Luo, Wen Wang, Ding Xu, Zixiang Huang, Wenlong Sun, Lei Zhao, Qin Yan, , Baosheng Feng

CMS improves sequencing uniformity and accuracy in non-canonical genomic regions by optimizing chemistry and enzymatic systems, reducing low-coverage bins and false negatives.

bioRxiv · Apr 28, 2026 · PreprintGenomics