Expression of the C-type lectin receptor CD205 on B cells mediates HIV-1 binding and trans infection of CD4+ T cells
Abigail D. Gerberick, Allison E. DePuyt, Peter E. J. Shoucair, Robbie B. Mailliard, Simon C. Watkins, Nicolas Sluis‐Cremer, Charles Rinaldo
This study identifies CD205 as a B cell receptor that facilitates HIV-1 binding and transfer to CD4+ T cells through CD40L/IL-4 stimulation.
bioRxiv · Aug 30, 2026 · PreprintMicrobiology