Author

Charlie DeFreest

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

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Emerson M. CarmonaiD· 1 shared Sharona E. GordoniD· 1 shared William N. ZagottaiD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperBiophysics

Emerson M. CarmonaORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintOct 2, 2026

Measuring protein conformational changes with genetically encoded bipyridylalanine and transition-metal ion FRET

Charlie DeFreest, Emerson M. Carmona, Sharona E. Gordon, William N. Zagotta

This paper introduces a method to adjust tmFRET distance sensitivity using different metal ions at a single bpyA-labeled protein site, enabling conformational change measurements.

DOI 10.64898/2026.10.01.756074

protein structureexperimental assay

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