Author

Charlie W Lees

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:fine-mapping· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Carl A Anderson· 2 shared Jack Satsangi· 2 shared Luke Jostins· 2 shared Miles ParkesiD· 2 shared Adrian Cortes· 1 shared Ailsa Hart· 1 shared Alison Simmons· 1 shared Andre FrankeiD· 1 shared

Activity by Year

2015-2017 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersGenetics

Carl A Anderson

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2 papers

Recent·Most cited

GeneticsNature GeneticsPeer-reviewedJan 9, 2017

Exploring the genetic architecture of inflammatory bowel disease by whole genome sequencing identifies association at ADCY7

Yang Luo, Katrina M de Lange, Luke Jostins…·Carl A Anderson

This study uses whole genome sequencing to explore the genetic architecture of inflammatory bowel diseases, identifying a risk variant in ADCY7 for ulcerative colitis but finding limited contribution of low-frequency variants to heritability.

DOI 10.1038/ng.3761

humanwhole-genome sequencing

𝕏 PostBluesky

GeneticsbioRxivOct 20, 2015

Association mapping of inflammatory bowel disease loci to single variant resolution

Hailiang Huang, Ming Fang, Luke Jostins…·International IBD Genetics Consortiu

This study fine-maps 94 inflammatory bowel disease loci to identify 45 causal variants with high confidence, providing insights into their functional impacts on disease mechanisms.

DOI 10.1038/nature22969

humanGWAS summary statistics

𝕏 PostBluesky